1,3-Di-sec-butyl carbodiimide
1,3-Di-sec-butyl carbodiimide
CAS: 66006-67-5
Molecular Formula: C9H18N2
1,3-Di-sec-butyl carbodiimide - Names and Identifiers
| Name | 1,3-Di-sec-butyl carbodiimide |
| Synonyms | Di-sec-butyl-carbodiimide 1,3-DI-(2-BUTYL)CARBODIIMIDE N,N'-dibutan-2-ylcarbodiimide N,N'-DI-SEC-BUTYLCARBODIIMIDE 1,3-DI-SEC-BUTYL CARBODIIMIDE N,N'-di-sec-butylcarbodiimide 1,3-Di-sec-butyl carbodiimide N,N'-Methanetetraylbis-2-butanamine 2-Butanamine, N,N'-methanetetraylbis- (9CI) (butan-2-yl)({[(butan-2-yl)imino]methylidene})amine |
| CAS | 66006-67-5 |
| InChI | InChI=1/C9H18N2/c1-5-8(3)10-7-11-9(4)6-2/h8-9H,5-6H2,1-4H3 |
1,3-Di-sec-butyl carbodiimide - Physico-chemical Properties
| Molecular Formula | C9H18N2 |
| Molar Mass | 154.25 |
| Density | 0.842g/cm3 |
| Boling Point | 68-68.5℃ (10 Torr) |
| Flash Point | 61.38°C |
| Vapor Presure | 0.69mmHg at 25°C |
| Refractive Index | 1.451 |
1,3-Di-sec-butyl carbodiimide - Introduction
1,3-Di-sec-butyl carbodiimide(1,3-Di-sec-butyl carbodiimide) is an organic compound with the chemical formula C10H18N2O.
It is a low-boiling organic solvent with a colorless or pale yellow liquid. It has a strong pungent odor and is soluble in common organic solvents such as ether and benzene. It has a low density, a melting point of -73°C and a boiling point of 188-190°C.
1,3-Di-sec-butyl carbodiimide is often used as a condensation reagent for amide compounds in organic synthesis. It can form very stable amide products by reaction with carboxylic acids. It can also be used as an activating reagent in the synthesis of polypeptide chains to convert carboxylic acid groups into more reactive ester groups. In addition, it can also be used in the synthesis of other organic compounds and drugs.
The preparation of 1,3-Di-sec-butyl carbodiimide is usually carried out by reacting diisobromopropanol with a cyanogen dehydrating agent to generate diisobutyl carbamyl, which is then oxidized with chlorine to generate the target product.
Because 1,3-Di-sec-butyl carbodiimide is irritating and has a damaging effect on the eyes, skin and respiratory tract, use should follow safe operating procedures and maintain good ventilation conditions. Avoid contact with skin and inhalation of its vapors. When used in the laboratory, wear chemical protective gloves, eye protection and protective clothing, and properly store the compound.
It is a low-boiling organic solvent with a colorless or pale yellow liquid. It has a strong pungent odor and is soluble in common organic solvents such as ether and benzene. It has a low density, a melting point of -73°C and a boiling point of 188-190°C.
1,3-Di-sec-butyl carbodiimide is often used as a condensation reagent for amide compounds in organic synthesis. It can form very stable amide products by reaction with carboxylic acids. It can also be used as an activating reagent in the synthesis of polypeptide chains to convert carboxylic acid groups into more reactive ester groups. In addition, it can also be used in the synthesis of other organic compounds and drugs.
The preparation of 1,3-Di-sec-butyl carbodiimide is usually carried out by reacting diisobromopropanol with a cyanogen dehydrating agent to generate diisobutyl carbamyl, which is then oxidized with chlorine to generate the target product.
Because 1,3-Di-sec-butyl carbodiimide is irritating and has a damaging effect on the eyes, skin and respiratory tract, use should follow safe operating procedures and maintain good ventilation conditions. Avoid contact with skin and inhalation of its vapors. When used in the laboratory, wear chemical protective gloves, eye protection and protective clothing, and properly store the compound.
Last Update：2024-04-09 21:04:16
